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This member is a YANA Mentor This is his Country or State Flag

Valery Krukov lives in Australia. He was 65 when he was diagnosed in February, 2016. His initial PSA was 4.70 ng/ml, his Gleason Score was 7, and he was staged Unknown. His choice of treatment was Other (Other). Here is his story.

Greetings,

My PSA jumped from 2.5 to 4.7 in one year, so I went thru MRI and prostate cancer has been found. That was February 2016. I went to Sydney and get an appointment with Prof. Philip Striker at St. Vincent Private.

One week later went thru biopsy and it was confirmed loud and clear that left side is clearly damaged. Only the solution has been offered to me is Da Vinci surgery and that was not something what I would like to do considering side effects after this procedure. Cost wasn't really a consideration while it was over $30k, but I could not see myself walking wearing nappies for the rest of my life and to have ED issues.

I asked for IRE (NanoKnife) but been told that my tumour is too big for this.

Then I contacted http://prostata-center.de in Germany and cut long story short on 9th of April 2016 they did work on me for 4 hours and left side is not there anymore. Very efficient centre: arrived to Frankfurt at 07:00, 09:30 at the centre, 10:30 MRI, 12:00 discussions with urologist. Next day at 14:00 as I was the last for a day or 4th patient and with my big one they put me last. Overnight in hospital, next day back to centre by taxi, get another MRI, check-up, instructions from doctor/nurse, received bag with medications and see you later.

Now I am still with catheter but that was my choice to go with it for 3 weeks instead of 2 weeks and in 3 months will know the results, as will do PSA test.

I shall update this in a week and tell you how it is feels without catheter, which is really annoying thing and the biggest issue after this procedure.

Regards,

Valery

UPDATED

May 2016

Hello,

Two day ago catheter is out and all functions are close to perfect.

Below is a report from the center.

Re: Mr. Valery Krukov, DOB 15/06/1950

The patient Valery Krukov contacted our institution seeking an alternative treatment after being confirmed of having prostate carcinoma Gleason score 7b (4-3) and Gleason score 6 (3+3),

The treatment that we are providing - Irreversible Electroporation of the Prostate - features several advantages: it may ablate selectively the confirmed cancerous areas, has remarkably fewer side-effects on the patient's well-being such as impotence and has not caused incontinence as yet. Before starting any of the below mentioned procedures, the patient was informed in detail about the method and has signed an informed consent in this regard.

At our institution the patient has undergone the following procedures:

Date Procedure Purpose

13.04.2016 MRI of the prostate with endorectal coil Restaging of the histologically confirmed prostate carcinoma Gleason 7b(4+3) and 6 (3+3) mainly on the left side. PI-RADS 6 in dorso-lateral outer zone on the left. Determining the exact location of the intraprostatic carcinomatous lesions to aid the planning of the focal IRE - therapy. General: Benigne Hyperplasia, chronicle inflammatory changes

14.04.2016 Prostate IRE-Treatment Ablation with 5 electrodes left side, antero medial, dorsal middle line, paramedian (directly adjacent to the urethra), lateral, as well as dorsal-lateral. Tumor volume is completely enclosed. Apikal IRE, moving the electrodes direction basal, followed by basal IRE
Intervention: Prof. Stehling, Urologist: Dr. El-Idrissi, Aneasthesiologist: Dr. Körbitzer, Assistant: Dr. Zapf, Ms Funk, Ms Reczkowski. Duration about 2 ˝ hours
15.04.2016 MRI of the pelvis without endorectal coil Immediate post-IRE-control of the pelvis - exclusion of possible complications i.e. bleeding, bladder perforation. Catheter should remain for at least 14 days (prostate is swollen after treatment, punctate hemorrhages where the electrodes were inserted. Everything normal)

After successful IRE - treatment the patient was discharged.

We recommend doing follow up MRI after three and six months and after one year. First PSA testing three months after treatment, then monitoring every three months in the beginning, every six months after one year.

UPDATED

May 2016

Greetings,

Today will be a week as catheter been removed for good!!!

Everything is working as before!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

Believe it or not!

Regards,

Valery

UPDATED

May 2016

Greetings,

It is wrong sequence but found my biopsy report prior to the treatment in Germany.

From:

NATA

Requested:

09/03/2016 PROF PHILLIP STRICKER 033426AL

Patient:

VALERY KRUKOV

DOB:

15/06/1950

Collected:

09/03/2016

HISTOPATHOLOGY REPORT : 19037-16MP

CLINICAL NOTES:

Rising PSA 4.5. Prostate biopsy x 18

MACROSCOPIC:

  1. Right posterior apex prostate biopsy. The specimen consists of three cores of cream tissue measuring between 8mm and 15mm in length. All embedded. (1 block)
  2. Left posterior apex prostate biopsy. The specimen consists of two cores of cream tissue measuring 14mm and 15mm in length. All embedded. (1 block)
  3. Right anterior apex prostate biopsy. The specimen consists of two cores of cream tissue measuring 5mm and 9mm in length. All embedded. (1 block)
  4. Left anterior apex prostate biopsy. The specimen consists of two cores of cream tissue measuring 8mm and 13mm in length. All embedded. (1 block)
  5. Right mid posterolateral prostate biopsy. The specimen consists of three cores of cream tissue measuring between 6mm and 13mm in length. All embedded. (1 block)
  6. Right mid posterior prostate biopsy. The specimen consists of two cores of cream tissue measuring 8mm and 15mm in length. All embedded. (1 block)
  7. Left mid posterior prostate biopsy. The specimen consists of two cores of cream tissue measuring 11mm and 14mm in length. All embedded. (1 block)
  8. Left mid posterolateral prostate biopsy. The specimen consists of two cores of cream tissue measuring 11mm and 13mm in length. All embedded. (1 block)
  9. Right base posterolateral prostate biopsy. The specimen consists of two cores of cream tissue measuring 13mm and 15mm in length. All embedded. (1 block)
  10. Right base posterior prostate biopsy. The specimen consists of three cores of cream tissue measuring between 7mm and 12mm in length. All embedded. (1 block)
  11. Left base posterior prostate biopsy. The specimen consists of three cores of cream tissue measuring between 5mm and 15mm in length. All embedded. (1 block)
  12. Left base posterolateral prostate biopsy. The specimen consists of three cores of cream tissue measuring between 6mm and 9mm in length. All embedded. (1 block)
  13. Left lateral prostate biopsy. The specimen consists of one core of cream tissue measuring 15mm in length. Embedded whole. (1 block)
  14. Right lateral prostate biopsy. The specimen consists of one core of cream tissue measuring 14mm in length. Embedded whole. (1 block)
  15. Right transitional zone prostate biopsy. The specimen consists of three cores of cream tissue measuring between 4mm and 19mm in length. All embedded. (1 block)
  16. Left transitional zone prostate biopsy. The specimen consists of two cores of cream tissue measuring 14mm and 16mm in length. All embedded. (1 block)
  17. Right anterior prostate biopsy. The specimen consists of one core of cream tissue measuring 15mm in length. Embedded whole. (1 block)
  18. Left anterior prostate biopsy. The specimen consists of one core of cream tissue measuring 12mm in length. Embedded whole. (1 block) JD2 Red

MICROSCOPIC:

  1. Right posterior apex prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  2. Left posterior apex prostate biopsy. Sections show adenocarcinoma Gleason score 3+4=7 present in both cores and involving 90% of the material.
  3. Right anterior apex prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  4. Left anterior apex prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  5. Right mid posterolateral prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  6. Right mid posterior prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  7. Left mid posterior prostate biopsy. Sections show adenocarcinoma Gleason score 3+4=7 present in one of the two cores and involving 40% of the core. There are features suspicious of extra prostatic extension.
  8. Left mid posterolateral prostate biopsy. Sections show adenocarcinoma Gleason score 3+4=7 present in both cores and involving 90% of the material.
  9. Right base posterolateral prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  10. Right base posterior prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  11. Left base posterior prostate biopsy. Sections show adenocarcinoma Gleason score 3+4=7 present in the larger of the three cores and involving 90% of that core.
  12. Left base posterolateral prostate biopsy. Sections show adenocarcinoma Gleason score 3+4=7 present in all three cores and involving 75% of the material in a discontinuous pattern. There is perineural infiltration plus features diagnostic of extra prostatic extension.
  13. Left lateral prostate biopsy. Sections show adenocarcinoma Gleason score 3+4=7 involving 40% of the core.
  14. Right lateral prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  15. Right transitional zone prostate biopsy. Sections show adenocarcinoma Gleason score 3+3=6 present in one of the three cores and involving 5% of that core.
  16. Left transitional zone prostate biopsy. Sections show adenocarcinoma Gleason score 4+3=7 present in one of the two cores and involving 40% of that core.
  17. Right anterior prostate biopsy. Sections show prostatic tissue containing no atypia or malignancy.
  18. Left anterior prostate biopsy. Sections show fibromuscular tissue.

SYNOPTIC REPORT FOR PROSTATE BIOPSIES

Tumour Type: Adenocarcinoma, NOS, acinar
Gleason Score: 3+4
Composite Gleason Score (ISUP 2005): 3+4=7
Highest Gleason Score (ISUP 2005): 4+3=7
% High Grade 4: 30%
Intraduct carcinoma: Absent
Location: Predominantly left plus focal right
Number of cores involved/Total: 12 of approximately 38
Perineural Invasion: Present
Vascular Invasion: Absent
Extraprostatic extension: Present

DIAGNOSIS:

PROSTATE BIOPSIES - ADENOCARCINOMA

Reported by Prof. Warick Delprado

UPDATED

July 2016

Hello, Today is 3 months since the treatment in Germany. PSA - 0.38 after 4.7 before. They saved 50% of prostate, so I believe that is a good result. MRI report will be available next week.

UPDATED

August 2016

Well, I got my MRI results and sent it by Australia Post (International Express), but it took 9 days instead of 2-4 business days, so arrived on last day before holidays in Germany. All I got from them at this stage: " today the CD and the report arrived and Prof. Stehling and Dr. El-Idrissi went through them. Everything fine and the PSA is very good." I shall get a proper and detail response after holidays.

Now next PSA test in 6 months and MRI in April 2017.

I very glad that took my chances and decided on IRE treatment in Germany!!!

UPDATED

October 2016

Hi, today got my PSA results ---- 0.27 ug/L !!! it is a drop of 0.11 from 3 months ago.

Next test will do in February 2017.

UPDATED

February 2017

Hi, just received PSA results - 0.31. I plan to have another one in May 2017 and MRI.

A new article "Why prostatectomy cannot cure prostate cancer" at: http://prostate-nanoknife.com/treatment_faq-treatment.html

Valery's e-mail address is: valery@freegate.net.au


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