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A Primer on Prostate Cancer
The Empowered Patient's Guide
by Stephen B. Strum, MD & Donna Pogliano

 

 

Table of Contents

How to Use This Book
An Overview
Chapter 1: How to Proceed
    Move Beyond Panic
    Synergize Your Efforts
    Understand Your Options
    Understand the Inherent Biases
    Know the Tempo of the Disease
    Choosing a Doctor and a Treatment
    Keep Meticulous Records
    Be Aware of the Financial Side of Your Illness
    Gathering Information
    Nuts and Bolts
    What You Should Have Learned from This Chapter
Chapter 2: The Basics of Prostate Cancer
    How Does Prostate Cancer Work?
    What You Should Have Learned from This Chapter
Chapter 3: Diagnosis and Testing
    The PSA and the Free PSA Percentage
    Digital Rectal Exam (DRE)
    Biopsy of the Prostate and the Gleason Score
    Prostatic Acid Phosphatase (PAP)
    ProstaScint Scan
    Endorectal MRI
    DNA Ploidy
    Positron Emission Tomography (PET) Scan
    Bone Scan
    CT (Computerized Tomography) Scan or CAT Scan
    Chromogranin A (CGA)
    Transforming Growth Factor Beta I (TGF-ß₁)
    What You Should Have Learned from This Chapter
Chapter 4: Treatment Options
    Radical Prostatectomy (RP)
        Pathological Examination
        Debulking the Tumor
        Addressing Lower Urinary Tract Symptoms
        Risk of Impotence
        Penile Shrinkage
        Dry Orgasms
        Incontinence
        Anastomotic Stricture
        Salvage Therapies
    Cryosurgery (Cryotherapy, Cryoablation)
        Cryosurgery Centers
        Cryosurgery Results
    Radiation Therapy (RT
        Advances in RT
        Overview
        Brachytherapy
        External Beam Radiation Therapy (EBRT)
    Androgen Deprivation Therapy (ADT)
        ADT Overview
    Watchful Waiting or Objectified Observation
    Chemotherapy of PC
    Treatments on the Horizon
        Aptosyn
        Provenge
        Angiostatin and Endostatin
        Atrasentan: An Endothelin Receptor Antagonist
        Oncolytic Viruses
        Antisense Oligonucleotides (ASO)
    Clinical Trials
    What You Should Have Learned from This Chapter
Chapter 5: What You Should Have Learned From This Primer
Afterword
Acknowledgments
Appendix A: Resources
    Introduction
    To Educate You and Provide Guidance
    To Contribute to your Knowledge Base
    To Communicate at a Higher Level with Your Medical Team
    To Create a Personalized Assessment of Your Status
    To Obtain Highly Focused Guidance
    To Ask Your Doctor Questions
    To Focus Further on Local Treatment Options
    To Resolve Treatment Side-Effects and Prevent Them
    To Employ Preventive and Wholistic Approaches
    To Further Your Assistance
Appendix B: If You Want To Know More
Appendix C: The Partin Tables
Appendix D: Glossary and TNM Staging Definitions
Appendix E: References
Appendix F: Useful Forms
    The Transrectal Ultrasound of the Prostate (TRUSP) Form
    The Diagnostic Biopsy Form
    The Biomarkers, Hormones, Bone Integrity and Other Labs Forms
    The AUA Symptom Score Form
    The Bone Scan Form
    The PC Laboratory Form
    The ProstaScint-CT Fusion Form
    The Endorectal MRI with Spectroscopy Form
    The Helpline Medical Form (HMF)
    The Flow Sheet Form
    The Summary Sheet and Surveillance Form
Appendix G: Clinical Stages of PC Illustrated
Appendix H: Figures, Tables, Physician's Notes, and Forms Listed
    List of Figures
    List of Tables
    List of Physician's Notes
    List of Forms
Index