PSA went from 2.5 in March 2008 to 5.29 in March 2009.
Biopsy showed the following results:
Your PSA was 5.29 August 14, 2009
Final pathologic diagnosis
A. Prostate, left, base, core needle biopsy: prostatic tissue with tiny focus of adenocarcinoma, Gleason Grade 3 + 3, involving 10% of the core.
B. Prostate, left, mid, core needle biopsy: prostatic adenocarcinoma, Gleason Grade 3+3, involving 10% of cores.
C. Prostate, left, apex, core needle biopsy: benign prostatic tissue.
D. Prostate, right, base, core needle biopsy: prostatic adenocarcinoma, Gleason Grade 3+3, involving 20% of cores.
E. Prostate, right, mid, core needle biopsy: prostatic adenocarcinoma, Gleason Grade 3+3, involving 5% of cores.
F. Prostate, right, apex, core needle biopsy: prostatic adenocarcinoma, Gleason Grade 3+3, involving 60% of cores.
I had surgery (RALP (Robotic Assisted Laparoscopic Surgery) in November 2009.
I was lucky, no incontinence and no other side effects.
My PSA results since surgery were as follows:
[All dates are shown in US format - Month/Date, so 1/7 is January 7, not First July]
01/07/2010 0.29
04/12/2010 0.28
07/20/2010 0.26
09/13/2010 0.29
03/21/2011 0.68
In May, June I had 37 radiation treatments (66Gy) ending on June 23, 2011. After radiation PSA continued to increase.
08/22/2011 1.58
10/03/2011 1.98
11/03/2011 2.65
12/02/2011 3.45
Now I am getting ready for ADT (Androgen Deprivation Therapy- Hormone therapy)
Bone Scan is negative, Bone density scan shows osteoporosis. I have stared Fosomax for bone density and Casodex to get ready for ADT (Lupron) I will have my first shot on December 19, shots monthly for three months and then go to a quarterly schedule.
After failed RP and RT, I finally started ADT in December 2011.
February 2012 was the first time since my prostate surgery in November 2009 that my PSA went down to < 0.1
I keep hoping ADT works and not have to go to next stage (chemo-therapy)
After having <.01 PSA in January and April of 2012, my last PSA reading went up to 0.28.
I had monthly Lupron Shots in December, January and February and switched to 3-month shot (22.5 units) of Lupron in May 2012. After the first three month shot my PSA went up. I am obviosuly concerned.
My oncologist believes this was just a "blip" and to stay the course. He does not recommend adding Casodex or Avodart for combination blockade, siting quality of life and possible side effects.
Only side effects I feel is hot flashes and feel good otherwise, working full time, walking etc.
My next Lupron shot is in August.
I started ADT (Lupron) in December 2011, fortunately my PSA has been <0.1 since then. Except for occasional hot flashes, I have no other side effects.
My last Lupron shot was in March 2013, my OC decided to skip the three-month shot in June 2013.
I am going for my next PSA test on 10/3/13, based on the result of that test I will decide to stay off (Intermittent ADT) or resume Lupron shots.
Since October 2013, I have been on Intermittent ADT, monitoring PSA and T-level every three months.
My PSA has stayed below 0.1 all this time. The protocol we are following is to take a Lupron shot when PSA goes above 2.0 or T-level goes above 50.
During my test was on 10/31/14, T-level was 131, I received a Lupron shot (22.5 units) in November 2014. My last test was on 1/30/15 and still waiting for my results. I have appointment with Oncologist on 2/23/15, at which time we will discuss and act on th results of last test.
I am not on any other medication (Avodart/Casodex etc.) and feeling good and lucky.
I am working full time and walk for exercise.
Since the last update, I have continued to be on Intermittent ADT, monitoring PSA and T-level every three months. PSA fortunately continues to be <0.1, the protocol is to receive a Lupron shot (22.5mg) if and when the T-level goes above 50.
I have received Lupron shots on 8/5/15, 11/4/15, 2/3/16 and 5/4/16.
I am staying healthy, working full time and walking 4 to 5 miles a day.
My last bone scan was on 3/2/15, increased activity was found in anterior right 7th rib and right femur. However, I am not in any pain.
Thank God.
I have not updated my story since I retired from my work (Griswold Controls) in June 2018.
Since then I have been on intermittent ADT, testing every three months, with protocol to take Lupron when testorone rises over 50.
My PSA had been <0.1 untill September 2019, it went to 0.2.
In November 2019 it went upto 0.4. Since then I have taken Lupron shot every three months on 10/22/19, 1/23/20 and 4/29/20, I am now due for my next shot.
Because the PSA is not going down, I went for MRI, CT Scan and PET Scan.
I have a 1.5 cm lesion in my prostate bed. No one knows how long it has been there, it could be there since my prostate cancer surgery in November 2009.
I was referred to a Radiation Oncologist who recommends SBRT (Sterotactic Body Radiation Treatment), which will apply targeted strong radiation to the lesion and hopefully cure it.
Insurance will not approve radiation until things get worse!
I took another blood test on 7/21, PSA still 0.4, and going for another PET Scan on 7/29.
Thankully, there is no metastasis, and I am not in pain. I am totally funtional and excercise and walk every day. Except for hot flashes, I ahve no other side effects.
Hemant's e-mail address is: hemantshah41 AT gmail.com (replace "AT" with "@")