AUGUST 2012---Pure chance, having none of the normal precursors of suspected PC, went to my GP complaining of feeling tired it would not be out of the norm for me to be in bed early evening and sleeping eight hours or so, my general appearance looking out of sorts. After the initial consultation it was deemed prudent to take a PSA test, at the time this meant nothing and thought nothing of it until horrors of horrors I was called back to the surgery as the result came back as 6.2 ng/ml. I was given the usual back passage examination and the doctor found the prostate of which she could reach lumpy, from this point on I cannot thank the NHS enough paper work was faxed to my local hospital (Basildon) I was in the evening having an MRI scan.

A few days later results came back as increasingly likely something was going on within the prostate, (sorry I have lost the notes to the actual terminology ) next up a biopsy was required to determine cancer or not, some three weeks later results where positive (again once I can find my notes I can update here)

Both left and right showing invasion of cancer cells and initial diagnostic of a T2 Gleason score 3+4 =7.

An appointment was arranged for the next step with the consultant as I had private health insurance I had a perfect opportunity to maximise my place and who for treatment choice by this time I had done a lot of research and I just said to the consultant that I want robotic surgery at Addenbrookes Hospital and that I want Professor David Neal an international renowned expert in PC and the DaVinci robotic technique.

I was admitted to hospital SEPTEMBER 2012 for robotic prostatectomy with nerve sparing, all went well with no pain management required and sent home next evening, catheter in place for ten days back to the hospital for removal and volume check of the bladder and make sure that I can pee the required amount all good so far.

LAB DIAGNOSES: pT3a specimen confined 3+4=7 Gleason-7 negative margins negative seminal vesicles.

What followed next was a complete surprise first PSA test OCTOBER 2012 came back at 0.02 excellent result, FEBRUARY 2013 PSA came back slightly higher 0.03 ( I always use the same lab for consistency ) mm I thought Professor Neal was not concerned, (I was of course as expected a level playing field of 0.01)

JUNE 2013 PSA elevated up to 0.13 conclusion biological recurrence, what the heck! I have no lymph node involvement negative margins, Professor Neal explained that I had a one centimetre nodule breaking out from the cover of the prostate and that because of this he had to remove one of the nerve bundles that was touching this LH side, so it appears it only takes one pesky cancer cell to escape and start growing.

AUGUST 2013 PSA 0.18 -- RADICAL RADIOTHERAPY TO THE PROSTATE BED -not worried soon kill off the pesky little buggers (my health by the way was excellent at this point with no incontinence and some 90% of erectile function available without any medication)

NOVEMBER 2013 PSA 0.11 NO RADIATION EFFECTS

FEBUARY 2014 PSA 0.06 all well and good keep to low carb high fibre diet, vitamin D, omega3, pomegranate Juice, broccoli, turmeric.

APRIL 2014 PSA 0.07, ok slight bounce no worries then to be expected.

AUGUST 2014 PSA 0.04, 4.5 kilometre walks most days keep on the diet not thinking about this pesky disease all positive running my own business so have something to work on and not worry about cancer.

OCTOBER 2014 PSA 0.1 -- OH DEAR NOT GOOD PROSTATE CANCER CELLS GROWING AGAIN NOT QUITE BEEN KILLED OFF BY RADIO THERAPY THEN!

FEBUARY 2015 PSA 0.12 -- some concern from me talking to the consultant, "not going to treat me just yet because of the side effects", all microscopic undetectable by normal measurements he says.

JUNE 2015 recent PSA test to be advised appointment with oncology.

A note to newly diagnosed patients and PSA all measurements is best carried out by using the super sensitive PSA; marker test BY THE SAME LAB for constancy if you had radical prostate surgery you should be at 0, Radio to the prostate you will have a measurement because in layman terms you still have a prostate producing PSA. Any rise after radical surgery can only be prostate cancer cells producing the enzyme hence an easy way to watch any progression through a simple blood test.

MY OWN THOUGHTS AND WHAT I THINK IS GOING ON: I believe I have micro metastatic prostate cancer cells growing somewhere, not at the prostate bed as this was radiated with precise measurements of where the T3A tumour was situated at which looking at the PSA; results kind of worked for a reduction of the PSA;, I will keep this page updated as I progress through the years,I was 54 years old at diagnoses now 57 years old and feeling good overall health is in good shape, and more importantly keeping positive on all fronts, started taking a new food supplement POMI-T worth a look up www.Pomi-T.com scientifically tested and developed here in the UK be interesting to see the PSA results! (radio therapy has effected erection function this month with a bit of leakage when coughing)

Regards Paul

24th JUNE 2015: PSA test come back at 0.27 up from 0.12 a PSA doubling time of 4 months, started taking PROMI-T four super foods packed into a capsual boosts the healthy polyphenois (Broccoli, Turmeric, Pomegranate, Green Tea) need to slow the rise of PSA.

Since my last update June 2015 PSA 0.27 I have progressed to a PSA level 0.7 (May 2016) this equates to a Doubling Time of 7.3 months, prognosis is reasonably good in that I am on AS with a view to treatment with ADT at the appropriate time, this may be a DT of 5 months or less. Apart from that no symptoms or sign of disease progression.

Just about a year on from my last update, still on active surveillance, with a PSA doubling time of 8.3 months with the last PSA test Nov 2016 coming in at 1.16, with no symptoms, the next visit to the oncologist March 2017. I do believe however that I do need to go into the attack whilst I have micro metises so I am going to ask to have my bollocks [British slang for "testicles"] removed, Testosterone the feeder of PCa cells, 95% removal within a couple of days. Don't fancy injections plus more side effects, not a cure but need to "buy" time before the inevitable happens and it's into the bone or elsewhere. Have to be realistic T3a tumours do not have happy outcomes a quick read through the stories here gives you an idea, so battle lines drawn diet in place, alcohol free, keeping fit let battle commence.

As of 15th March PSA has risen to 1.72 which gives me a doubling time of 8 months, on 9th of March I had a NM Bone whole body scan with results of NEGATIVE Mets, which at low PSA level was to be expected, showed hot spots of genetic wear and tear in hip, shoulder, knees, ankles wrists- reason for scan was pain LH hip.

So good news on the mets - according to Addenbrooks Treatment starts at level PSA10 and that would be the usual Hormone therapy. However my target is to extend the PSA doubling time, so going to go on the Cannabis oil treatment. Will post my chart and methods with PSA tests here. Will be interesting to see if the treatment is viable. Catch up three months time.

A big thank you to Mark Freedkin who kindly converted the PDF I submitted to JPEG of the PSA active surveillance since surgery to the present month /year. Previously I stated that instead of waiting around until the PSA reaches 10 to then treated with ADT, I intend to be pro-active as the goal here is to reduce PSA and consequently doubling time- Method: RSO Cannabis oil THC65 CBD65.

Searching the internet there seems to be a connection in using this Rick Simpson Oil to reducing tumours and in some cases get rid of the cancer all together. Dennis Hill was a T4 Prostate Cancer diagnosed and he says cured himself of this disease with clinical pathology to back up his claims, any way not for me to judge but considering "what have you got to lose" attitude. I will give it a go.

This brings me on to the chart the treatment will start with a PSA lab result of 1.72 calculated to be from Feb16 -Feb 17 7months DT, I will submit charts with PSA results going forward to see what can be achieved currently. I am tested every 3 months using the same lab for consistency, this I hope will give sufferers of this disease some sort of understanding, hope, "other treatments off the radar" a way of moving forward just for clarity. Surgery was 2012- relapse 2013 Radation -2014 PSA rising again to the present day of this submission.

Quick update on the "Pot Oil" treatment, having purchased 10ml of this concentrated Cannabis oil i am on 0.002 to start with as your body needs to get used to the THC effects, now after a bit of trial and error i have found a ratio of 20/1 coconut oil/cana oil works well inserted via the rectum this means you are able to process 70% rather than orally which is 20% as the liver comes into play and causes more of a high, the intention is to double up every two weeks to a final daily dose of 0.5ml THC1-1CBD. PSA RESULTS JUNE 2017.

CANNABIS OIL KILLS PROSTATE CANCER even STAGE4 worth a look guys nothing to loose have you!! story below Alan Park: July 20, 2014
"Hey there. I'm the real deal.
I enjoy a fantastic state of health since May after being written off in December by my expert, top notch prostate MD. Twit. ...
If they don't like the way I used it, they can shove it up their ass. That's what I did.
I took Rick Simpson oil, embedded it in coconut butter and shoved it where my clueless MD likes to put his finger.
Stuck it right to my prostate.
Good god, that stuff is more gooey than a rom-com.
Anyhow, no more cancer.
They can shove that up their ass too.

CANNABIS CURES CANCERS!
21 July 2014 ·
How Alan Park Cured His Cancer With Cannabis Oil
- Parts 1 - 6
(1:05:00)
Published on September 11, 2014
This is an interview with Alan Park, a comedian who you might know from the Air Farce on CBC, or from various televised comedy shows.
He cured his cancer using cannabis oil. No, really.
... his story is compelling and you should listen to the whole thing.
"He says you have a PSA, which is the Prostate Specific Antigen, this is the reading they get ya to see how you're doing ... and if you're at a 1 or 1 & 1/2 or 2, 2 & 1/2 or 3 ... if you're getting around 4, you want to look at that, there might be some preventative things you can do before it pops out of control.
And 5, 6, 7 on up to 10 ... oh boy, you're in trouble, things are not going well ... and he tells me:
'You have a 700.'
Whoa! Ha! I started laughing, every time I think about it now ... it's like if you went to the grocery store and rounded up all your stuff, at some health food store that's expensive, and they go: 'That's 4.3 trillion dollars.'
Ha-ha ... I better put the greens back, holy shit! ...
So what am I supposed to do with this?
700?
It sounds like a death sentence, it sounds like I died last week!
What are you talking about?!"
- Alan Park
Five months later, Alan's PSA was 1.19.

http://medicalmarijuana.co.uk/cannabis-and-prostate-cancer-the-stories-of-dusty-frank-and-alan-park/

After three months of being on the cannibis oil, the prostate cancer cells have a doubling time of just two months, you will see the leg up from 1.72 (March) to 3.56 (June) indicates a huge jump from my normal seven months. Conclusion using the oil has increased testosterone levels significantly and as we know Prostate Cancer cells use it to grow.

Bone scan shows no mets, CT scan booked next phase is CASODEX ADT. I'll post back on results going forward but outcome is terminal and I will live my life accordingly. This is being realistic as I am 59 years old and quite young for Prostate Cancer to take hold.

Added chart , CRT scan this week along with another PSA test, ADT next line of treatment, depending on result, cannabis oil undesirable side effect over three months a jump from 1.72 to 3.56 never had such a jump before as been steady since 2012.

2nd of August- CT scan picked up enlarged Lymph Node -pelvis area. PSA 4.26 ng/ml good spot by the guys at Addinbrookes Hospital at this low level of PSA that last spike prompted the scan, as of this date started Bicalutamide (Casodex) 150mg. Prognosis five years give or take.

Great news, three months on ADT and down to post operation PSA level, in other words undetectable, what a result 150mg Casodex. Consultation 1st November.

Quick update now around six months ADT no side effects PC is hormone sensitive - now undetectable - delighted with that.

Major update: Restaging chest abdomen and pelvis including bone scan showed SINGLE enlarged 16mm x11mm left EXTERNAL ILIAC NODE , ADT has suppressed the PSA enough to undetectable levels however with activity in this node the NHS have put me into a small select study for the use of SABR (Stereotactic Ablative Radio Therapy) for limited spread of cancer (Oligometastases) or Cyber Knife.

I have since receved five days of targeted therapy to the node with the view to destroy it along with the cancer, with all this in mind it will be interesting to watch the PSA - next update will be August 2018.

Three consecutive ultra-sensitive PSA tests over the past nine months have come back UNDETECTABLE. ADT plus CyberKnife therapy to one external iliac pelvic node showing activity - all good.

Super Sensitive PSA UNDETECTABLE - next update January 2019, ADT has effected my "Zest" for life, feeling withdrawn and not wanting to do much, bit of a fight to get motivated, not depressed but energy levels are low. Four consecutive undetectable PSA readings now very happy with that.

Update: have been undetectable PSA for around 10 months or so since ADT treatment and Cyber Knife to one Iliac Node- since stopping ADT over three months the PSA has risen to 0.66 - next stop waiting game then Scanner to find where the mets is occuring then on to ADT as my PC cells are sensitive to Testestorone .

Update - PSA doubling up every 1.3 months mets to node or nodes.

PSA 4.2 after 10 months - (taken off ADT) confirmed NODEL after bone and body scan - back onto ADT as I do have a very positive result once this kicks in 150mg Casodex last time out undetectable. Seven years since surgery - I've been lucky. Will update in December.

It now seems that I have metastic lymph node castrate resistant PCa - back on Casodex there was a drop to 0.05 radation to left nodal area no change now three months later 0.65. Will update once I've seen oncoligist.

Happy New Year, update as follows PSMA-PET SCAN 25/11/2020 shows tracer avidivity in multiple lymph nodes meaning disease progression.

Note: PSA 1.61 - STARTED LHRHa Prostap 11.25mg plus 50mg Casodex.

Covid-19 vaccine then onto chemotherapy to mop up.

Left and Right hip replacement-not prostate cancer relatedlater in the year.

Fatigued (hormone related) no other symptons.

March 2021 for next injection and PSA reading.

Update: 09/03/21 three months on from the first 3-monthly LHRHa hormone injection PROSTAP 11.25mg PSA has fallen from 1.61 to 0.29 .

Quick update - Xtandi 160mg a day added to the ADT.

A quick up date to the above -after four weeks of XTANDI, the psa has dropped to a remarkable 0.04, just above post surgery levels September 2012. Oncoligist to advise on the next steps as I was supplied with 30 days worth at four tablets a day. Prostap 3 amd 50mg Casodex carries on. This after PSMA-PET shows extensive nodal disease.

As from 04/05/21 back on to XTANDI (12 weeks) as a positive result from the initial four week course as above. Also a number of blood tests on the 4th at the start of the 12 week course and at the end keeping a check on everything during this regime of Xtandi.To point out anyone taking this drug it does knock you side ways, side eeects of restless sleep, zombie like feeling NO ENERGY NO INTEREST -and what can only be described as intense on off headaches during the night lingering into the morning, i found keeping hydrated helped into the third week with the odd pain killer on the worse of it.

Quick update bloods now show undetectable as of 4/05/21 - restarted full blockade 06/

Enzalutamide/Prostap3/Bicalutamide-PSA measured on super sensitive essay <0.02 (undetectable) since last update. Considering PSMA PET-SCAN showed disease progression to multiple lymph nodes with mHSPC sensitive prostate cancer.

Undetectable <0.04 six months on treatment 160mg Enzalutamide (Xtandi), 50mg Bicalutamide,Prostap 3 injection (leuprorelin acetate) 11.25mg every three months.

Side effects NONE- since i was reporting fatigue on first use for three months or so.

Recent total hip replacement , developed shingles blood count slightly abnormal so going to have another set of bloods in three weeks.

Considering multiple lymph invasion shown up on PSMA-pet i call the above a result.

Quick update, PSA rising from undetectable levels, Xtandi no longer in control of keeping the cancer in check, also severe headache lasting 24/7 past six weeks or so in connection with high blood preasure topping out at 240/130 , glad to say just a few days in after stopping Xtandi blood preasure comming down to 144/100 in combo with BP meds. Having a chat with oncology in three weeks for the next chapter in this evolving saga of PROSTATE CANCER. ps: 22nd June Albert Hall a PC UK charity event looking forward to it.

Xtandi, appears to have stopped working now, Oncology consultants today for the next steps.

Rising PSA doubling every three months , had a PSMA -pet scan showing two lymph nodes behind the tummy with activity PSA currently 12.72 up from 3.06 at the begining of this year, next step is the Chemotherapy route so just waiting for the referral to my local hospital to begin treatment.

Apart from this feeling fine overall.

As of this dated up date now on the seventh round of Chemo out of ten, long story short hit 33 PSA in October 2023, results on the chemo exellent from this date now 0.8.

Quick update on going Chemo 9th session PSA 0.42

All stable as of this date---

Another quick update- all stable PSA:0.04

Paul's e-mail address is: paul AT belainteractive.co.uk (replace "AT" with "@")