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Hi I live in Pittsburgh, PA and just got the call from the Urologist a week ago. PSA has been rising the last 5 years from 2.2 to 2.4 to 3.0 and now 3.8. This acceleration concerned my PCP enough to refer me to Urologist. I have a meeting with him this week to discuss options. PCa was found in 2/12 cores, less than 5% of each core. Gleason score 3+3 in each. PSA tested twice in July 4.2 and then 3.8 a week later with Free PSA 21%. I am classified as Stage 1. I also suffer from an enlarged prostate so not sure how that might enter into into my options. I will update after my meeting with him.

I am 58 years old, and fairly active. 5-10" and weigh 178. Diagnosed a year ago, Stage T1c. PSA is up only slightly to 4.4 from 4.2, so basically unchanged. Doctor recommended active surveillance a year ago and sees no reason to change that now as I am considered low risk. In July 2017, Gleason was 3+3 on 2 out of 12 cores, less than 5% of each core considered cancerous. I am to have another PSA test in 3 months and another biopsy in 6 months which would be 18 months from the initial biopsy. We plan to over-sample the side where cancer was found.

I have not gone for a second opinion as I doubt I would get advice that is different at this point. If the PSA starts to rise and the biopsy worsens, then I will seek one.

59 years old. Diagnosed 2 years ago, 2017. PSA remains at low levels, 4.1. First Biopsy in 2017 revealed 2 cores, 5%, 3+3. Second biopsy in Feb 19 reveals one core, 5%, 3+3. Verified by Johns Hopkins Urology. Active Surveillance continues. Thinking of discussing options with another urologist.

Been on active surveillance for 2 years. Just got back new PSA reading at 5.3, up from 3.8 in October 2018. Concerned about the rate of change in less than a year. Even though biopsy still shows 2 cores at 5%, Gleason 3+3, I am thinking it is time to go get a surgeons opinion at a world class healthcare facility here in Pittsburgh on long-term treatment options. My urologist is a brachytherapy guy so time to get another perspective, particularly as I am 59, diagnosed at 57. Cannot help think that the randomness of the biopsy procedure could be missing something more serious. I am in good shape so I think surgery might be the best option. Any thoughts from members would be appreciated.

Hello everyone, I was diagnosed 2 years ago 8/17 at 57 years old with 2/12 cores at Gleason 3+3, 5% each core. Had a follow up biopsy in 2/19 and showed only one core at 5%. Such is the randomness of of the biopsy. After 2 years of active surveillance, was concerned about the PSA rise from 3.8 in 10/18 to 5.3 in 8/19. Finally decided to get a second opinion in 10/19 from a leading University of Pittsburgh surgeon as I was leaning hard toward getting a RALP while I am still a "young" 59 years of age. Surgeon recommended that I get a multiparametic MRI and another PSA in Feb 2020, a year after my last biopsy. I guess he is saying that we should continue to monitor all of this. I really liked him as his credentials are fantastic. However, I can't help but think that I need to take care of this as I don't want this to get away from me, but the risks of side effects are nothing to discount. Such is the conundrum of active surveillance. Thanks to all of you who have provided me with advice. I will wait until next year for the MpMRI and another PSA and we will see if that leads to a fusion guided biopsy. He seems to be not too worried with my PSA at 5.3 and a 60 gram enlarged prostate with a 3+3 cancer.

Jeff's e-mail address is: jkozmo AT gmail.com (replace "AT" with "@")

NOTE: Jeff has not updated his story for more than 15 months, so you may not receive any response from him.